Performance and structure of single-mode bosonic codes

The early Gottesman, Kitaev, and Preskill (GKP) proposal for encoding a qubit in an oscillator has recently been followed by cat- and binomial-code proposals. Numerically optimized codes have also been proposed, and we introduce new codes of this type here. These codes have yet to be compared using the same error model; we provide such a comparison by determining the entanglement fidelity of all codes with respect to the bosonic pure-loss channel (i.e., photon loss) after the optimal recovery operation. We then compare achievable communication rates of the combined encoding-error-recovery channel by calculating the channel's hashing bound for each code. Cat and binomial codes perform similarly, with binomial codes outperforming cat codes at small loss rates. Despite not being designed to protect against the pure-loss channel, GKP codes significantly outperform all other codes for most values of the loss rate. We show that the performance of GKP and some binomial codes increases monotonically with increasing average photon number of the codes. In order to corroborate our numerical evidence of the cat/binomial/GKP order of performance occurring at small loss rates, we analytically evaluate the quantum error-correction conditions of those codes. For GKP codes, we find an essential singularity in the entanglement fidelity in the limit of vanishing loss rate. In addition to comparing the codes, we draw parallels between binomial codes and discrete-variable systems. First, we characterize one- and two-mode binomial as well as multi-qubit permutation-invariant codes in terms of spin-coherent states. Such a characterization allows us to introduce check operators and error-correction procedures for binomial codes. Second, we introduce a generalization of spin-coherent states, extending our characterization to qudit binomial codes and yielding a new multi-qudit code.Comment: 34 pages, 11 figures, 4 tables. v3: published version. See related talk at https://absuploads.aps.org/presentation.cfm?pid=1351

Intelligence of very preterm or very low birthweight infants in young adulthood

Contains fulltext : 80142.pdf (publisher's version ) (Closed access)OBJECTIVE: To examine the effect of intrauterine and neonatal growth, prematurity and personal and environmental risk factors on intelligence in adulthood in survivors of the early neonatal intensive care era. METHODS: A large geographically based cohort comprised 94% of all babies born alive in the Netherlands in 1983 with a gestational age below 32 weeks and/or a birth weight >1500 g (POPS study). Intelligence was assessed in 596 participants at 19 years of age. Intrauterine and neonatal growth were assessed at birth and 3 months of corrected age. Environmental and personal risk factors were maternal age, education of the parent, sex and origin. RESULTS: The mean (SD) IQ of the cohort was 97.8 (15.6). In multiple regression analysis, participants with highly educated parents had a 14.2-point higher IQ than those with less well-educated parents. A 1 SD increase in birth weight was associated with a 2.6-point higher IQ, and a 1-week increase in gestational age was associated with a 1.3-point higher IQ. Participants born to young mothers (<25 years) had a 2.7-point lower IQ, and men had a 2.1-point higher IQ than women. The effect on intelligence after early (symmetric) intrauterine growth retardation was more pronounced than after later (asymmetric) intrauterine or neonatal growth retardation. These differences in mean IQ remained when participants with overt handicaps were excluded. CONCLUSIONS: Prematurity as well as the timing of growth retardation are important for later intelligence. Parental education, however, best predicted later intelligence in very preterm or very low birthweight infants

HerMES: Current Cosmic Infrared Background Estimates Can be Explained by Known Galaxies and their Faint Companions at z < 4

We report contributions to cosmic infrared background (CIB) intensities originating from known galaxies and their faint companions at submillimeter wavelengths. Using the publicly-available UltraVISTA catalog, and maps at 250, 350, and 500 {\mu}m from the \emph{Herschel} Multi-tiered Extragalactic Survey (HerMES), we perform a novel measurement that exploits the fact that uncatalogued sources may bias stacked flux densities --- particularly if the resolution of the image is poor --- and intentionally smooth the images before stacking and summing intensities. By smoothing the maps we are capturing the contribution of faint (undetected in K_S ~ 23.4) sources that are physically associated, or correlated, with the detected sources. We find that the cumulative CIB increases with increased smoothing, reaching 9.82 +- 0.78, 5.77 +- 0.43, and 2.32 +- 0.19$\, \rm nW m^{-2} sr^{-1}$ at 250, 350, and 500 {\mu}m at 300 arcsec FWHM. This corresponds to a fraction of the fiducial CIB of 0.94 +- 0.23, 1.07 +- 0.31, and 0.97 +- 0.26 at 250, 350, and 500 {\mu}m, where the uncertainties are dominated by those of the absolute CIB. We then propose, with a simple model combining parametric descriptions for stacked flux densities and stellar mass functions, that emission from galaxies with log(M/Msun) > 8.5 can account for the most of the measured total intensities, and argue against contributions from extended, diffuse emission. Finally, we discuss prospects for future survey instruments to improve the estimates of the absolute CIB levels, and observe any potentially remaining emission at z > 4.Comment: Accepted to ApJL. 6 Pages, 3 figure

Effect of zoledronic acid on the doxycycline-induced decrease in tumour burden in a bone metastasis model of human breast cancer

Bone is one of the most frequent sites for metastasis in breast cancer patients often resulting in significant clinical morbidity and mortality. Bisphosphonates are currently the standard of care for breast cancer patients with bone metastasis. We have shown previously that doxycycline, a member of the tetracycline family of antibiotics, reduces total tumour burden in an experimental bone metastasis mouse model of human breast cancer. In this study, we combined doxycycline treatment together with zoledronic acid, the most potent bisphosphonate. Drug administration started 3 days before the injection of the MDA-MB-231 cells. When mice were administered zoledronic acid alone, the total tumour burden decreased by 43% compared to placebo treatment. Administration of a combination of zoledronic acid and doxycycline resulted in a 74% decrease in total tumour burden compared to untreated mice. In doxycycline- and zoledronate-treated mice bone formation was significantly enhanced as determined by increased numbers of osteoblasts, osteoid surface and volume, whereas a decrease in bone resorption was also observed. Doxycycline greatly reduced tumour burden and could also compensate for the increased bone resorption. The addition of zoledronate to the regimen further decreased tumour burden, caused an extensive decrease in bone-associated soft tissue tumour burden (93%), and sustained the bone volume, which could result in a smaller fracture risk. Treatment with zoledronic acid in combination with doxycycline may be very beneficial for breast cancer patients at risk for osteolytic bone metastasis

Have we seen all the galaxies that comprise the cosmic infrared background at 250 µm ≤λ≤ 500 µm?

The cosmic infrared background (CIB) provides a fundamental observational constraint on the star formation history of galaxies over cosmic history. We estimate the contribution to the CIB from catalogued galaxies in the COSMOS field by using a novel map fitting technique on the Herschel SPIRE maps. Prior galaxy positions are obtained using detections over a large range in wavelengths in the Ks–3 GHz range. Our method simultaneously fits the galaxies, the system foreground, and the leakage of flux from galaxies located in masked areas and corrects for an ‘overfitting’ effect not previously accounted for in stacking methods. We explore the contribution to the CIB as a function of galaxy survey wavelength and depth. We find high contributions to the CIB with the deep r (mAB ≤ 26.5), Ks (mAB ≤ 24.0), and 3.6 μm (mAB ≤ 25.5) catalogues. We combine these three deep catalogues and find a total CIB contributions of 10.5 ± 1.6, 6.7 ± 1.5, and 3.1 ± 0.7 nWm−2 sr−1 at 250, 350, and 500 μm, respectively. Our CIB estimates are consistent with recent phenomenological models, prior based SPIRE number counts and with (though more precise than) the diffuse total measured by FIRAS. Our results raise the interesting prospect that the CIB contribution at λ≤500μm from known galaxies has converged. Future large-area surveys like those with the Large Synoptic Survey Telescope are therefore likely to resolve a substantial fraction of the population responsible for the CIB at 250 μm ≤ λ ≤ 500 μm

HELP: Star formation as a function of galaxy environment with Herschel

The Herschel Extragalactic Legacy Project (HELP) brings together a vast range of data frommany astronomical observatories. Its main focus is on the Herschel data, which maps dustobscured star formation over 1300 deg2. With this unprecedented combination of data sets, it is possible to investigate how the star formation versus stellar mass relation (main sequence)of star-forming galaxies depends on environment. In this pilot study, we explore this question within 0.1 2. We also estimate the evolution of the star formation rate density in the COSMOS field, and our results are consistent with previous measurements at z 2 but we find a 1.4+0.3-0.2 times higher peak value of the star formation rate density at z ~ 1.9

Provision of artificial shelter on beaches is associated with improved shorebird fledging success

Artificial chick shelters might improve productivity of beach-nesting birds threatened by anthropogenic disturbance. We investigated the efficacy of three different chick shelter designs against four criteria: accessibility to chicks over time, thermal insulation, conspicuousness to beach-goers, and practicality (cost and ease of transport). One design (&lsquo;A-frame&rsquo;) was selected because it offered the greatest thermal insulation, was the least conspicuous, most cost effective, and performed equally well in terms of accessibility. We deployed these artificial shelters on Hooded Plover Thinornis rubricollis territories where broods were present (n 5 11), and compared the behaviour and survival rate of chicks to that at control sites (n 5 10). We were unable to discern any difference in the behaviour of broods when artificial shelters were available. However, the survival rate of chicks to fledging was 71.8% higher where an artificial shelter was provided (n 5 21 broods). This was validated by analysing data from a larger sample of broods monitored as part of an active volunteer-based management programme; shelters conferred a 42.8%increase in survival to fledging (n 5 81 broods). Thus, artificial shelters have the potential to increase survival rates of threatened shorebird chicks, though the mechanisms through which survival is increased require further investigation

280 GHz Focal Plane Unit Design and Characterization for the SPIDER-2 Suborbital Polarimeter

We describe the construction and characterization of the 280 GHz bolometric focal plane units (FPUs) to be deployed on the second flight of the balloon-borne SPIDER instrument. These FPUs are vital to SPIDER's primary science goal of detecting or placing an upper limit on the amplitude of the primordial gravitational wave signature in the cosmic microwave background (CMB) by constraining the B-mode contamination in the CMB from Galactic dust emission. Each 280 GHz focal plane contains a 16 x 16 grid of corrugated silicon feedhorns coupled to an array of aluminum-manganese transition-edge sensor (TES) bolometers fabricated on 150 mm diameter substrates. In total, the three 280 GHz FPUs contain 1,530 polarization sensitive bolometers (765 spatial pixels) optimized for the low loading environment in flight and read out by time-division SQUID multiplexing. In this paper we describe the mechanical, thermal, and magnetic shielding architecture of the focal planes and present cryogenic measurements which characterize yield and the uniformity of several bolometer parameters. The assembled FPUs have high yields, with one array as high as 95% including defects from wiring and readout. We demonstrate high uniformity in device parameters, finding the median saturation power for each TES array to be ~3 pW at 300 mK with a less than 6% variation across each array at one standard deviation. These focal planes will be deployed alongside the 95 and 150 GHz telescopes in the SPIDER-2 instrument, slated to fly from McMurdo Station in Antarctica in December 2018